LA Rams vs. Arizona Cardinals NFL Pick Prediction 12/13/2021 by Tony T.
Rams at Cardinals—Rams will be without starting running back Darrell Henderson. Center Brian Edwards doubtful. Rams broke a three game losing streak with the 37-7 home win to Jacksonville Jaguars. Defense struggled during that three game losing streak allowing an average of 32 points a game. Arizona has won two straight with the 33-22 road win at Chicago Bears. Game was played in bad weather. Cardinals defense trending well past three games holding teams to 313 yards with 5.7 yards per pass attempt and 37.5% conversion rate on third down. Rams have had struggles going on the road facing elite teams failing to cover 12 of their past 15 against teams with a 80% or greater winning percentage. LA had lost and failed to cover two straight at Green Bay and San Francisco. Rams had failed to cover five straight until their win against a down Jacksonville team. Kyler Murray is healthy for the Cardinals. This is his second game back from injury and should be sharper in this spot. In his first meeting against the Rams, Murray completed 75% of his throws for 268 yards and 8.4 yards per attempt in a 37-20 road win. Play Arizona -2.5.