San Francisco 49ers vs. Cincinnati Bengals NFL Pick Prediction 12/12/2021 by Tony T.
49ers at Bengals—San Francisco running back Mitchell out. Questionable is wide receiver Samuel. Bengals back Mixon and wide out Higgins questionable. Burrow with that finger has been limited in practice. He is also dealing with a knee issue. Two starting linebackers out and a corner questionable. San Francisco had their three game win streak snapped in a 30-23 road defeat at Seattle. 49ers run game grounded for only 71 yards Cincinnati has lost three of four at home with the 44-21 home defeat to LA Chargers. 49ers trending better past three games as they are putting up 373 yards a game with 223 passing for 8.6 yards per pass attempt. Defense for the 49ers in that period holding teams to 283 yards, 4.4 yards per rush along with 6.1 per pass attempt. In this period the Bengals are allowing 3.7 sacks a game and it was a bad performance by the Bengals offensive line. 49ers defense and poor line of the Bengals difference here. As are the injuries on defense for Cincinnati along with Burrow playing through ailments. Play San Francisco -1.5.